Lower extremity chronic limb-threatening ischemia (CLTI) is the most advanced form of peripheral arterial disease (PAD). Historically, development of CLTI was associated with 1-year amputation rates of 25 % and a 5-year mortality of >50 % [1]. The key components of CLTI management are symptom control, wound care, and revascularization with the goal of functional limb salvage and improved survival and quality of life [2–3]. The institution of a multidisciplinary care (MDC) team aims to improve outcomes in CLTI [4], in particular amputation-free survival (AFS) [5].