Blood Pressure (BP) values fluctuate over time around average values, as a consequence of the interaction between multiple intrinsic and environmental factors affecting the cardiovascular system [1]. The effectiveness of the body physiological regulatory mechanisms that contribute to the maintenance of homeostasis declines with aging, leading to altered variability patterns, including higher Blood Pressure Variability (BPV), an emerging typical condition of older adults [2]. Over the past decade, increasing interest in BPV has led to repeated evidence of its independent predictive value for negative health outcomes associated with aging, ranging from neurological and cardiovascular events to metabolic disorders [3–5].
