December 2013
Volume:
24
Number:
8
Journal Articles
36 Articles
Cardiovascular Medicine
Regional fat distribution and cardiometabolic risk in healthy postmenopausal women
28 October 2013
Abstract: Background: Regional fat distribution is an important determinant of cardiometabolic risk after menopause. The aim of the present study was to investigate the association between indices of... more
Association of adiponectin with peripheral muscle status in elderly patients with heart failure
7 October 2013
Abstract: Background: Reduced peripheral muscle mass was demonstrated in patients with chronic heart failure (HF). Adipokines may have potent metabolic effects on skeletal muscle. The associations... more
Cardiovascular mortality in Hispanics compared to non-Hispanic whites: A systematic review and meta-analysis of the Hispanic paradox
4 October 2013
Abstract: Background: Hispanics, the largest minority in the U.S., have a higher prevalence of several cardiovascular (CV) risk factors than non-Hispanic whites (NHW). However, some studies have... more
Joint use of cardio-embolic and bleeding risk scores in elderly patients with atrial fibrillation
16 September 2013
Abstract: Background: Scores for cardio-embolic and bleeding risk in patients with atrial fibrillation are described in the literature. However, it is not clear how they co-classify elderly patients... more
Platypnea–orthodeoxia syndrome in the elderly treated by percutaneous patent foramen ovale closure: A case series and literature review
5 September 2013
Abstract: Background: Platypnea–orthodeoxia syndrome (POS) is a rare clinical phenomenon, associating normal oxygen saturation in a supine position and arterial hypoxemia in an upright position. This... more
Impact of gender–age interaction on the outcome of ischemic stroke in an Italian cohort of patients treated according to a standardized clinical pathway
3 September 2013
Abstract: Background: Stroke outcome has been reported as worse in women, especially in terms of disability. As for mortality, the data are conflicting, with some reports suggesting a female... more
Gastroenterology and Hepatology
The genotype C could play a key role in hepatitis B virus associated nephritis among the Northwest Chinese children
28 August 2013
Abstract: Background: Hepatitis B virus-associated glomerulonephritis (HBV-GN) is a kind of immune complex-induced glomerulonephritis. The present study was designed to determine whether Hepatitis B... more
Epidemiology and molecular analysis of hepatitis A, B and C in a semi-urban and rural area of Crete
28 August 2013
Abstract: Aim: An observational seroepidemiological study was carried out in a well-defined primary-care district on the island of Crete in order to determine the recent endemicity of viral hepatitis... more
Incidence and prevalence of inflammatory bowel diseases in gastroenterology primary care setting
17 July 2013
Abstract: Background: The incidence of inflammatory bowel diseases (IBDs) has markedly increased over the last years, but no epidemiological study has been performed in gastroenterology primary care... more
Predictive factors of risk of hepatocellular carcinoma in chronic hepatitis C
12 July 2013
Abstract: Objective: To identify risk factors associated with the development of HCC and develop a score to identify high risk subgroups.Methods: We conducted a follow-up study, with biannual... more
Dental enamel defects in adult coeliac disease: Prevalence and correlation with symptoms and age at diagnosis
8 April 2013
Abstract: Background: Coeliac disease is a condition characterized by a wide spectrum of clinical manifestations. Any organ can be affected and, among others, dental enamel defects have been... more
General Internal Medicine
The Mugello Study, a survey of nonagenarians living in Tuscany: Design, methods and participants' general characteristics
14 October 2013
Abstract: Background: Previous studies on nonagenarians have widely investigated functional and cognitive decline, falls, predictors of mortality, inflammation and aging genetics. However, some... more
Discharge intervention pilot improves satisfaction for patients and professionals
30 September 2013
Abstract: Background: The risk of adverse events and information loss following hospital discharge is particularly high for vulnerable multimorbid patients. Poor coordination of care at discharge... more
Quality of transitions in older medical patients with frequent readmissions: Opportunities for improvement
20 September 2013
Abstract: Background: Medical patients with a recent previous hospitalisation are at very high risk of subsequent readmission. Evidence suggests that improving key transition processes may reduce... more
Clinical characteristics and prognostic significance of serum albumin changes in an internal medicine ward
6 September 2013
Abstract: Background: The prognostic significance of hypoalbuminemia and the dynamic changes in serum albumin during hospitalization in internal medicine wards has not been sufficiently investigated.... more
Differential characteristics in polypathological inpatients in internal medicine departments and acute geriatric units: The PLUPAR study
12 August 2013
Abstract: Aim: To determine whether there are any differences between polypathological patients attended in Internal Medicine departments and acute Geriatric units.Methods: A cross-sectional... more
Transcatheter aortic valve implantation in nonagenarians: Effective and safe
9 August 2013
Abstract: Background: The number of nonagenarians is rising dramatically. These patients often develop severe aortic stenosis for which transcatheter aortic valve implantation (TAVI) is an attractive... more
Characteristics and outcome in nonagenarians admitted in general internal medicine and other specialties
30 July 2013
Abstract: Summary: To describe the characteristics of nonagenarians admitted to the surgical and medical divisions at a tertiary hospital and compare them with nonagenarians admitted to other... more
Prevalence and clinical characteristics of the DSM IV major depression among general internal medicine patients
1 July 2013
Abstract: Objective: The aim of this study was to investigate the prevalence and clinical characteristics of the DSM IV major depressive disorder (MDD) among patients admitted to the General Internal... more
Osteonecrosis of the jaws in patients assuming oral bisphosphonates for osteoporosis: A retrospective multi-hospital-based study of 87 Italian cases
14 June 2013
Abstract: Background: Bisphosphonates (BPs) are currently the chief drugs for the prevention/treatment of osteoporosis; one of their adverse effects is the osteonecrosis of the jaw (BRONJ). The... more
Letters to the Editor
Maxillomandibular advancement in obstructive sleep apnea syndrome
22 November 2013
Mannarino and colleagues published in this journal an interesting review article on the obstructive sleep apnea syndrome (OSAS) . They enlisted several therapeutic options of this syndrome that, if... more
The early mortality associated with agitation and sedation in acutely ill medical patients
18 September 2013
The UK and Ireland have recently introduced a National Early Warning Score (NEWS) as part of the routine assessment of patients . NEWS is determined from the patient's heart and breathing rate, blood... more
Screening interval for celiac disease in patients with type 1 diabetes mellitus
22 August 2013
We read with great interest the article by Bakker et al. . They made a retrospective evaluation of 118 patients with both type 1 diabetes mellitus (T1DM) and celiac disease (CD). They collected data... more
Awareness of hepatitis B virus reactivation among physicians authorized to prescribe chemotherapy
15 August 2013
The risk of chronic hepatitis B virus (HBV) reactivation under the influence of chemotherapy is being increasingly recognized with an incidence ranging from 20 to 80% in patients who are positive for... more
C-reactive protein as a prognostic factor in elderly patients with aspiration pneumonia
10 July 2013
Most cases of pneumonia in the elderly are caused by aspiration . Many advanced countries are rapidly aging, and the presence of aspiration pneumonia has been recognized as one of the significant... more
On colonoscopy in acute colonic pseudo obstruction
8 July 2013
Acute colonic pseudo obstruction (ACPO) is a rare but life threatening condition of massive colonic dilatation in the absence of mechanical obstruction. It occurs almost exclusively in patients with... more
Narrative Reviews
Systemic amyloidoses: What an internist should know
20 November 2013
Abstract: Systemic amyloidoses are rare, complex diseases caused by misfolding of autologous proteins. Although these diseases are fatal, effective treatments exist that can alter their natural... more
Why glucocorticoid withdrawal may sometimes be as dangerous as the treatment itself
27 June 2013
Abstract: Glucocorticoid therapy is widely used, but withdrawal from glucocorticoids comes with a potential life-threatening risk of adrenal insufficiency. Recent case reports document that adrenal... more
Clinical indications for the albumin use: Still a controversial issue
24 June 2013
Abstract: Human serum albumin (HSA) is the most abundant circulating protein and accounts for about 70% of the plasma colloid osmotic pressure. Beside the well known capacity to act as plasma-... more
Pulmonary involvement in Fabry disease: Overview and perspectives
3 June 2013
Abstract: Fabry disease (FD) is an X-linked lysosomal storage disorder caused by deficiency of alpha-galactosidase A, which leads to storage of sphingolipids in virtually all human cells and... more
Circadian rhythms and medical diseases: Does it matter when drugs are taken?
23 April 2013
Abstract: Background: Chronobiology is devoted to the study of biological rhythms. It is possible that a given medication may be therapeutic and safe when administered at some time, but... more
Osteoporosis treatment: Focus on safety
22 April 2013
Abstract: Osteoporosis results in approximately one-half of older white women and one-third of men sustaining fractures, which cause significant disability and increased mortality. Interventions are... more
The role of Helicobacter pylori infection in hematological disorders
25 March 2013
Abstract: Helicobacter pylori (H. pylori) is a Gram-negative spiral bacterium, classified as a carcinogen of class I, according to the World Health Organization (WHO). The infection is a major cause... more
Pneumology
Extrapulmonary tuberculosis: 7year-experience of a tertiary center in Istanbul
12 September 2013
Abstract: Background: Although a decreasing trend of tuberculosis (TB) was reported in Turkey, higher proportion of extrapulmonary tuberculosis (EPT) was revealed.Material and methods: In this... more
Prognosis of multi-lobar pneumonia in community-acquired pneumonia: A systematic review and meta-analysis
10 June 2013
Abstract: Background: Pneumonia is the leading cause of infection related mortality. Multilobar pneumonia (MLP) may have poorer outcomes and is a constituent of some prognostic indices. Our aim was... more
Rheumatology and Immunology
Clinical significance of autoantibodies to the pericentromeric heterochromatin protein 1a protein
4 November 2013
Abstract: Ojective: The objective of the study is to determine the frequency and the clinical significance of autoantibodies to the pericentromeric heterochromatin protein 1 (HP1). So far this... more