Published: 28 September 2020
Author(s): Marco Vincenzo Lenti, Antonio Di Sabatino
Issue: January 2021

Coeliac disease is a high-prevalent, immune-mediated, chronic enteropathy caused by the ingestion of gluten in genetically susceptible individuals [1,2]. From the clinical viewpoint, coeliac disease is a proteiform condition, spacing from the complete lack of signs or symptoms to a severe malabsorption syndrome characterised by steatorrhea, weight loss, anaemia, hypo-proteinemia, and electrolyte imbalance. In most cases, complete and long-life withdrawal of gluten from the diet is able to revert villous atrophy.

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