Published: 25 November 2021
Author(s): Anna Staudt, Rudolf A. Jörres, Thilo Hinterberger, Nadine Lehnen, Thomas Loew, Stephan Budweiser
Issue: January 2022

Since the beginning of the COVID-19 pandemic in 2020, in Germany almost 3.8 million inhabitants have been positively tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1], and 91,803 inhabitants have been reported as having died from or in association with SARS-CoV-2 [2]. The spectrum of clinical signs and manifestations ranges from asymptomatic, mild influenza-like signs such as fever, cough and sore throat to severe pneumonias with respiratory failure, multi-organ failure and death [3–8].

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