There is a strong relationship between high blood pressure (BP) and the risk of developing chronic kidney disease (CKD) [1–8]. In people with CKD, a high BP is associated with a faster decline of kidney function towards end-stage kidney disease (ESKD) [9,10]. However, treatment of hypertension to prevent CKD progression or ESKD has shown varying results. Thus, randomization to intensive systolic BP (SBP) lowering did not slow the progression of CKD in the Modification of Diet in Renal Disease (MDRD) [11–13] or in the African American Study of Kidney Disease and Hypertension (AASK) [14,15].
