June 2019

18 Articles

No Section

Porphyrias: A clinically based approach

27 June 2019
Author(s): Joana Rigor, Sara Almeida Pinto, Daniela Martins-Mendes

Porphyrias are a group of metabolic diseases, individually rare but with an important combined prevalence. Because of their pathological complexity and clinical heterogeneity, they present a... more

Patients with acute pulmonary embolism at intermediate risk for death: Can we further stratify?

24 June 2019
Author(s): Cecilia Becattini, Ludovica Anna Cimini, Maria Cristina Vedovati

International Scientific Societies (European Society of Cardiology, American Heart Association, American College of Chest Physician) recommend stratification for the risk of short-term death to drive... more

Does my patient really need this at admission? Seven opportunities for improving value in patient care during their hospitalization

20 June 2019
Author(s): Luis Corral-Gudino, Alicia Rivas-Lamazares, Ana González-Fernández, Miriam Rodríguez-María, Carmen Aguilera-Sanz, Ana Tierra-Rodríguez, Paula Runza-Buznego, Ester Hernández-Martín, Martín Ortega-Gil, Alberto Bahamonde-Carrasco

Besides the main treatment for their disease, hospital patients receive multiple care measures which include venous lines (VL), urinary catheters (UC), dietary restrictions (DR), mandatory bed rest (... more

An update on IgG4-related lung disease

19 June 2019
Author(s): Angelica Torres Morales, Andrea Guerrero Cignarella, Isma Safayeth Jabeen, Jamie S. Barkin, Mehdi Mirsaeidi

IgG4-related disease (IgG4-RD) is an autoimmune disorder characterized by substantial infiltration of plasma cells with IgG4 in target organs. Lung manifestations predominantly present as... more

Outcomes in acute medicine - Evidence from extended observations on readmissions, hospital length of stay and mortality outcomes

10 June 2019
Author(s): Richard Conway, Declan Byrne, Deirdre O'Riordan, Bernard Silke

The Acute Medical Admission Unit (AMAU) model of care has been widely deployed, we examine changes in hospital readmission rates, length of stay (LOS) and 30-day in-hospital mortality over 16 years.

Internal Medicine Flashcard

White islands in a sea of red: A tropical rash

11 June 2019
Author(s): Josephine Anne Lucero, Danielle Benedict Sacdalan

A 32-year-old male from the Philippines presented with a three-day history of high-grade fever (Tmax 39.8C) refractory to acetaminophen and NSAIDs. It was accompanied by headache, anorexia, and... more

An atypical cause of dyspnea

5 June 2019
Author(s): Charlotte Kaeuffer, Marie-Pierre Ledoux, Raoul Herbrecht

A 53-year old woman was admitted to hospital with a six-month history of cough and dyspnea, weight loss and left abdominal and lumbar pain. Inspiratory crackles were diffusely heard during physical... more

Letter to the Editor

Skin autofluorescence as a tool for cardiovascular risk estimation in patients with rheumatoid arthritis

25 June 2019
Author(s): S.H. Bakker-Aling, J.M. van Woerkom, T.P. Zomer, H.C.J.L. Buscher, T. van Bemmel

Rheumatoid arthritis (RA) is associated with increased cardiovascular mortality and morbidity [1,2]. Most studies among RA patients were performed in an era in which RA could only be suboptimally... more

Non-invasive positive pressure ventilation in pneumonia outside ICU. Can it be definitely justified?

1 June 2019
Author(s): Antonello Nicolini, Teresa Diaz de Teran, Elena Barbagelata, Antonio Esquinas

We have read with great interest the manuscript “Non-invasive positive pressure ventilation in pneumonia outside Intensive care Unit. An Italian multicenter observational study” by AM Brambilla et al... more

Narrative Review

Paraneoplastic movement disorders: phenomenology, diagnosis, and treatment

12 June 2019
Author(s): Martina Chirra, Luca Marsili, Simone Gallerini, Elizabeth G. Keeling, Roberto Marconi, Carlo Colosimo

Paraneoplastic syndromes include, by definition, any symptomatic and non-metastatic condition associated with a neoplasm. Paraneoplastic movement disorders are a heterogeneous group of syndromes... more

Original Article

Lung ultrasonography in pulmonary tuberculosis: A pilot study on diagnostic accuracy in a high-risk population

22 June 2019
Author(s): M. Montuori, F. Casella, G. Casazza, F. Franzetti, P. Pini, C. Invernizzi, D. Torzillo, G. Rizzardini, M. Galli, C. Cogliati

The validity of lung ultrasound (LUS) in the diagnosis of interstitial or focal lung pathologies is well documented, we assessed its accuracy in the diagnosis of pulmonary tuberculosis (PTB).

Increased risk of venous thromboembolism among patients with hyperthyroidism: a systematic review and meta-analysis of cohort studies

19 June 2019
Author(s): Sutat Srisawat, Tullaya Sitasuwan, Patompong Ungprasert

Studies have suggested that patients with hyperthyroidism may have a higher risk of venous thromboembolism (VTE) compared to individuals with normal thyroid function, although the data is quite... more

Short-term effects of direct-acting antiviral agents on inflammation and gut microbiota in hepatitis C-infected patients

17 June 2019
Author(s): Patricia Pérez-Matute, María Íñiguez, María J. Villanueva-Millán, Emma Recio-Fernández, Aitana Morano Vázquez, Sheila Castro Sánchez, Luís E. Morano, José A. Oteo

Liver damage is associated with gut dysbiosis. New direct-acting antiviral agents (DAAs) are able to eradicate hepatitis C virus (HCV) from the body. However, the short and medium-term effects of... more

Vedolizumab is effective and safe in real-life treatment of inflammatory bowel diseases outpatients: A multicenter, observational study in primary inflammatory bowel disease centers

14 June 2019
Author(s): Antonio Tursi, Giammarco Mocci, Roberto Faggiani, Leonardo Allegretta, Nicola Della Valle, Antonio de Medici, Giacomo Forti, Marilisa Franceschi, Antonio Ferronato, Sara Gallina, Giuseppina Grasso, Tiziana Larussa, Francesco Luzza, Roberto Lorenzetti, Antonio Penna, Stefano Rodino', Ladislava Sebkova, Angelo Lauria, Simona Piergallini, Giuseppe Pranzo, Stefano Scorza, Costantino Zampaletta, Marcello Picchio, Walter Elisei

Italian data currently available in managing ulcerative colitis (UC) and Crohn's disease (CD) patients with vedolizumab (VDZ) are coming just from secondary and tertiary centers. The present study... more

Cardiac autonomic modulation at rest and during orthostatic stress among different systemic sclerosis subsets

12 June 2019
Author(s): Gabriel Dias Rodrigues, Eleonora Tobaldini, Chiara Bellocchi, Alessandro Santaniello, Monica Caronni, Adriana Severino, Marco Froldi, Lorenzo Beretta, Pedro Paulo da Silva Soares, Nicola Montano

To compare autonomic heart rate variability (HRV) parameters at rest and during active stand in a population of SSc patients, taking into account SSc subsets age-matched to healthy control subjects.

ST-elevation myocardial infarction in a real world population - An observational retrospective study with a sex perspective

11 June 2019
Author(s): Vojko Kanic, David Suran, Igor Krajnc, Gregor Kompara

Mortality after myocardial infarction is higher in women than in men. Data on the association between sex and mortality are conflicting and inconclusive. We evaluated whether there is a sex... more

External validation of the CACE-HF risk score for mortality in patients with heart failure

11 June 2019
Author(s): R. Quirós-López, L. Manzano-Espinosa, A. Bilbao, M. Montero Pérez-Barquero, J.M. Cepeda-Rodrigo, A. Escobar-Martínez

To validate externally the CACE-HF clinical prediction rule, which predicts 1-year mortality in patients with heart failure (HF).

Special Article

JAK inhibitors in 2019, synthetic review in 10 points

6 June 2019
Author(s): Romain Muller

JAK inhibitors are recent treatments. Many publications have appeared in recent years, exposing treatment efficiencies in phases 2 and 3 studies, or their tolerance profile in various rheumatological... more


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