Diabetes of the exocrine pancreas (DEP), - also defined as pancreatic, pancreatogenic, or type 3c diabetes - arises from the structural or functional loss of insulin secretion secondary to exocrine pancreatic diseases [1,2]. The most common etiologies of DEP are acute and chronic pancreatitis (CP) followed by pancreatic ductal adenocarcinoma [2]. The widely accepted pathophysiology for DEP is insulin deficiency, with two potential mechanisms responsible for relative or absolute insulin deficit: the inflammatory environment and extensive fibrosis of the exocrine pancreas [2].
