September 2021
28 ArticlesNo Section
Low bleeding and thromboembolic risk with continued dabigatran during cardiovascular interventions: the GLORIA-AF study
Non vitamin-K-antagonist oral anticoagulants (NOACs) have emerged as preferred treatment over vitamin K antagonists (VKAs) for the prevention of stroke in patients with nonvalvular atrial... more
Predictors of cardiovascular events in patients with primary systemic vasculitis: A 5 years prospective observational study
: Granulomatosis with polyangiitis (GPA) is one of antineutrophil cytoplasmic autoantibody (ANCA) – associated systemic vasculitis and is characterised by inflammation of blood vessels. Systemic... more
Epidemiology of sarcoidosis in northern Spain, 1999-2019: A population-based study
Sarcoidosis is a multisystem disease of unknown etiology characterized by the formation of non-caseating granulomas [1]. Sarcoidosis primarily affects the lungs and lymphatic system, but any organ... more
Both lean and fat body mass associate with blood pressure
The positive relationship of body mass index (BMI) with blood pressure (BP) has been demonstrated in several large-scale observational studies [1–8]. Importantly, a causal association between BMI and... more
Very low lipoprotein(a) and increased mortality risk after myocardial infarction
Lipoprotein(a) (Lp[a]) consists of a lipoprotein moiety identical to low density lipoprotein (LDL) cholesterol, as well as a plasminogen-similar glycoprotein apo(a). About 90% of a person's Lp(a)... more
The 3Ds – Discussion, diagnosis and direction: Elements for effective obesity care by healthcare professionals
Obesity is a chronic disease associated with multiple health complications [1]. Furthermore, the COVID-19 pandemic has made evident the impact obesity can have on health outcomes, whereby people with... more
Commentary
How body composition may influence 24 hours blood pressure
In the last 10 years a global increase in risk exposure for attributable death has been observed for several factors, including ambient particulate matter pollution, drug use, high fasting plasma... more
Unexpected high mortality associated with very low lipoprotein(a) after acute myocardial infarction: Identifying the unknown
Plasma or serum concentrations of lipoprotein(a) - Lp(a) - are an established marker of risk for atherothrombotic cardiovascular disease (CVD) and for degenerative aortic valve stenosis (1).... more
Closing obesity care gaps and achieving health equity for people living with obesity
Lack of access to obesity care is contributing to health inequalities for people living with obesity [1,2]. Public health systems have not established obesity care paths and there is insufficient... more
Anti Ro52 antibodies: One step further, but still not there yet
The term extractable nuclear antigens (ENAs) is a historical denomination, though still in use, derived from the observation that several antigens from the cell nuclei are soluble and can be isolated... more
Corrigendum
Corrigendum to: Associations of proton pump inhibitors and hospitalization due to hyponatremia: A population–based case–control study. Eur J Intern Med. 2019 Jan;59:65-69
The authors regret that in preparation of a new article based on the same data as in the previous published article [1], we unfortunately discovered two errors in the dataset. Some cases of... more
Internal Medicine Flashcard
Itchy papular and nodular skin lesions in chronic kidney disease patient
A 65-year-old man with a history of obesity, type 2 diabetes mellitus (DMT2) for more than 10 years, stage 3b chronic kidney disease (CKD) and hypertension was admitted to our internal medicine ward... more
Letter to the Editor
Comment to: Non-specific clinical presentations are not prognostic and do not anticipate hospital length of stay or resource utilization: Author's reply
We thank Bingisser and colleagues for their interest in our article “Non-specific clinical presentations are not prognostic and do not anticipate hospital length of stay or resource utilization” [1,2...
The possibility of heart failure in patients with “Pneumonia” -Author's reply
H. Ito provided a letter to the editor discussing our recently published study on electrolyte disorders in patients presenting to the emergency department with community-acquired pneumonia (CAP) [1... more
Primary adrenal insufficiency associated with Oxford-AstraZeneca ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia (VITT)
Dear editor,
The link between nutritional status and outcomes in COVID-19 patients in ICU: Is obesity or sarcopenia the real problem?
Obesity is frequent among COVID-19 patients and data indicate that this condition is associated with poor outcomes [1]. Nutritional status, in particular in COVID-19 patients in intensive care unit (... more
Comment to: Non-specific clinical presentations are not prognostic and do not anticipate hospital length of stay or resource utilization
Dear Sir,
Wearing a mask does indeed matter: Lessons from the 2021 influenza infection season
Until recently, wearing masks, a long-term custom in Japan during the winter flu season and during early springtime to protect against Japanese cedar pollinosis was not common in everyday life in... more
Vaccine-induced thrombotic thrombocytopenia, a rare but severe case of friendly fire in the battle against COVID-19 pandemic: What pathogenesis?
We have read with great interest two recent contributions to the Clinical Insights section of the Journal concerning reports of thromboembolic complications associated with the administration of the... more
Risk factors of recurrence in patients with cancer-associated venous thromboembolism
The following other authors from the COMMAND VTE Registry Investigators participated the study: Syunsuke Saga, MDa; Kazushige Kadota, MDb; Toru Takase, MDc; Seiichi Hiramori, MDd; Kitae Kim, MDe;... more
Dynamics of high-sensitivity troponin T and myocardial dysfunction during the first 72 h of septic shock
Cardiomyopathy is frequently associated with septic shock, despite divergences in type and severity of cardiac alterations making difficult the management of these patients. Different studies have... more
Diagnosis of hepatitis C-related liver disease in patients with mild hemophilia
Following the contamination of blood products with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) in the 1970s to 1980s, almost all hemophilia patients who received plasma-derived... more
The possibility of heart failure in patients with “pneumonia”
Dear Editors,
Original Article
Laryngotracheal aspiration test reduce the false negative rate in patients with suspected SARS-COV-2 pneumonia despite a negative nasopharyngeal swab
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic is undermining the ability of many emergency departments (EDs) to accurately diagnose and isolate novel coronavirus disease (... more
Incident atrial fibrillation and its risk prediction in patients developing COVID-19: A machine learning based algorithm approach
Multi-morbidity is associated with adverse health outcomes and healthcare costs, especially among the elderly [1,2]. Preliminary evidence suggests that multi-morbidity is associated with confirmed... more
Clinical significance of anti-Ro52 (TRIM21) antibodies in adult patients with connective tissue diseases
Connective tissue diseases (CTD) – rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Sjögren syndrome (SS), systemic sclerosis (SSc), idiopathic inflammatory myopathies (IIM), mixed... more
Patient motivation to lose weight: Importance of healthcare professional support, goals and self-efficacy
Obesity is a global health concern [1]. Multiple complications are associated with overweight and obesity including diabetes, heart disease, musculoskeletal disorders and some cancers, and people... more
Review Article
Obesity as an adipose tissue dysfunction disease and a risk factor for infections – Covid-19 as a case study
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV2) disease (COVID-19) is a novel threat that hampers life expectancy especially in obese individuals. Though this association is clinically... more