We read with interest the recent article of Giacomelli et al. [1], who showed that the main characteristics of patients hospitalised with coronavirus disease 2019 (COVID-19) have substantially evolved throughout the course of the ongoing pandemic, reporting a significant increase of patients with milder clinical phenotype. This finding has exceptional importance for influencing future healthcare policies, though it does not reliably mirror the evolution of clinical severity of COVID-19 within the general population.
