We thank Jin et al [1] for the comment on methodological considerations regarding our study [2]. The observation of a higher mean eGFR in the DOAC group after propensity score matching (PSM) deserves attention since eGFR is a clinically relevant determinant of both anticoagulant pharmacokinetics and patient outcomes. However, the relatively wide standard deviations reported for eGFR in both groups suggest substantial overlap in renal function distributions, which may attenuate the clinical relevance of the observed mean difference.
