We read with interest the study by Zuin and colleagues reporting the STAMP score for predicting 48-hour clinical deterioration in hemodynamically stable patients with intermediate-high-risk acute pulmonary embolism (PE). The score integrates five admission variables (age ≥65 years, chest pain, syncope, TAPSE/PASP ≤0.33, and mean arterial pressure ≤81.5 mmHg) and demonstrated good discrimination in both derivation and validation cohorts [1]. Risk refinement for this subgroup remains clinically important, and the newly released AHA/ACC multisociety guideline underscores ongoing efforts to improve prognostic assessment and align risk labels with actionable pathways [2].
