Published: 21 April 2026
Author(s): Elias Giallafos, Ioannis Ilias, Evaggelos Oikonomou, Ourania Katsarou, Gerasimos Siasos
Issue: April 2026
Section: Letter to the Editor

Sarcoidosis (SA) is a multisystem granulomatous disease with a highly variable clinical course. To-date, there are no validated circulating biomarkers capable of reliably predicting long-term outcome in SA [1]. Identifying accessible, routinely measurable metabolic indices that could improve risk stratification in SA therefore represents an unmet clinical need of considerable importance.

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