Published: 5 February 2020
Author(s): Cécile M. Yelnik, Yann Nguyen, Véronique Le Guern, Eric Hachulla, Marc Lambert
Section: Letter to the Editor

As recently written by Cruz and coll., antiphospholipid antibodies (aPL) are frequently found in immune thrombocytopenia (ITP) and are not associated with specific clinical feature [1]. Similarly, thrombocytopenia is frequently reported in APS patients and is one of the most common non-criteria manifestations of the disease. Underlining pathological mechanisms of thrombocytopenia in APS are various, and mostly not related to definite ITP. In the life-threatening variant of APS, called the catastrophic APS (CAPS), thrombocytopenia is due to a thrombotic microangiopathy characterized by the occurrence of thrombosis in multiple organs over a short period of time [2].

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