Nowadays, systemic thrombolysis remains the cornerstone in the treatment of different life-threatening arterial occlusive disease as ischemic stroke and pulmonary embolism (PE). Conversely, its use has scale down over the years in the treatment of acute myocardial infarction (AMI) after the wide diffusion of percutaneous coronary artery intervention (PCI) and Cath-labs [1]. Thrombolytic treatments have been widely investigated both from a clinical and biochemical point of view [2]. However, the rheological properties of thrombolytic agents are often not well known or ignored by physicians since their description require the understanding of complex mathematical models.