Published: 8 May 2026
Author(s): Francesco Bertoldo, Giulia Sartori, Matteo Lombini, Alberto Fantin, Ernesto Crisafulli
Issue: May 2026
Section: Letter to the Editor

Obstructive sleep apnea (OSA) is a highly prevalent disorder characterized by recurrent upper airway collapse, intermittent hypoxemia, and sleep fragmentation [1]. Beyond its established cardiometabolic consequences, increasing evidence suggests a role for OSA in bone metabolism alterations [2,3]. However, the relationship between OSA severity and skeletal fragility remains inconsistent across studies, likely reflecting limitations of the apnea-hypopnea index (AHI) as a measure of disease burden [3,4].

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