Published: 11 May 2026
Author(s): Ludovica Anna Cimini, Maria Cristina Vedovati
Issue: May 2026
Section: Commentary

Pulmonary embolism (PE) is traditionally considered an acute cardiovascular emergency, with management strategies primarily aimed at reducing early mortality and secondarily at preventing recurrence [1]. While short-term outcomes after PE are well described, the role of PE in influencing long-term survival remains debated. In particular, it remains uncertain whether the increased long-term mortality after PE is driven by the embolic event itself or by the burden of underlying comorbidities and patient frailty [2].

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