Amyloidosis is a storage disease caused by the extracellular deposition of fibers derived from structural alterations of unstable proteins, which after folding and aggregation are finally deposited in tissues, producing structural and functional alterations. The two proteins with the greatest affinity for affecting the heart are immunoglobulin light chains, which cause primary amyloidosis, also known as immunoglobulin light chain amyloidosis (AL), and transthyretin (TTR), which causes TTR amyloidosis (ATTR)[1].
