Fumagalli et al. [1] examined depressive symptoms in older patients undergoing electrical cardioversion for persistent atrial fibrillation (AF) and identified associations with clinical complexity and physical performance. In 258 patients with a mean age of 78 years, higher depressive symptom scores were associated with lower Short Physical Performance Battery (SPPB) scores. In the subgroup with available interleukin-6 (IL-6) measurements, depressive symptoms were also associated with higher IL-6 levels [1].
