I read with great interest the article by Clerici and colleagues titled "Left atrial enlargement and 1-year cerebrovascular events in subjects without atrial fibrillation: A prospective cohort study," recently published in the European Journal of Internal Medicine. This large-scale prospective cohort study provides valuable evidence that left atrial enlargement (LAE), assessed by left atrial volume index (LAVi), is independently associated with short-term cerebrovascular events in individuals without known atrial fibrillation or ongoing anticoagulation.
