Sarcoidosis is a multisystem granulomatous disease with high variability and sometimes unpredictable behavior. This great variability necessitates the search for clinical patterns of observed phenotypic variables to help in care management [1-3]. However, definition of a true phenotype requires a consistent natural history, similar clinical and physiological characteristics, underlying pathobiology with identifiable biomarkers and genetics, and a predictable response to general and specific therapies [4].
