The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an unprecedented health emergency, causing over 125 million confirmed cases and over 2.5 million deaths worldwide as of March 2021 [1]. Understanding the long-term immunological response in infected individuals will be central in defeating the COVID-19 pandemic, and understanding humoral kinetics, timing, and persistence of SARS-CoV-2 antibodies after natural infection, will be essential to ensure an appropriate vaccination strategy.