We read with great interest the multicentre analysis by Bartalucci and colleagues, who evaluated sex-based differences and 30-day mortality in 1132 adults aged 65 years or older with Candida bloodstream infection (BSI) [1]. Their study provides a timely message for clinicians: despite more comorbidities and more frequent septic shock at onset among men, biological sex was not independently associated with short-term mortality. Instead, age, comorbidity burden, septic shock, antifungal treatment, and source control dominated prognosis [1].
