We read with interest the study by Carlucci et al., “Eosinophil-linked pulmonary circulation in EGPA Improves under anti-IL-5/R therapy: A longitudinal study” [1]. The authors should be commended for exploring a clinically relevant and insufficiently studied aspect of eosinophilic granulomatosis with polyangiitis (EGPA): the relationship between eosinophilic inflammation, pulmonary vascular load, and right ventricular–pulmonary artery (RV–PA) interaction. Cardiopulmonary involvement remains one of the most consequential manifestations of EGPA, and the possibility of detecting subclinical abnormalities by echocardiography is clinically attractive.
