Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare, multisystemic vasculitis that primarily affects small to medium-sized blood vessels. It is characterized by a well-defined triad of asthma, eosinophilia, and systemic vasculitis, often leading to severe organ involvement [1]. Eosinophils are thought to play a central role in EGPA pathogenesis through direct tissue injury and inflammatory signaling [2]. A variety of cytokines, chemokines, and toxic proteins released by these cells (such as IL-4, IL-5, IL-9, IL-13, and IL-25) [3] contribute to disease progression.
