Hyperuricemia (HU) is a prevalent chronic metabolic condition characterized by elevated serum uric acid (SUA) levels [1]. The accumulation of monosodium urate crystals in joint and extra-articular tissues can ultimately result in cartilage and muscle degeneration [2]. The most widely known clinical manifestations of HU are acute gout flares [3] and nephrolithiasis [4], both associated with elevated SUA level, along with the chronic tissue damage caused by chronic urate crystal deposition [5,6]. However, even asymptomatic HU patients may develop silent tissue damage [7].
