We read with great interest this population-based study derived from the Stockholm sodium cohort [1], which examined the association between early sodium correction rates in severe hyponatraemia and subsequent osmotic demyelination syndrome (ODS) as well as other neuropsychiatric outcomes. Leveraging a large laboratory-linked registry with long-term follow-up, the authors address an important and long-debated clinical question. Nevertheless, several methodological and interpretative issues merit further discussion.
