October 2018
25 ArticlesNo Section
Indoor air pollution exposure effects on lung and cardiovascular health in the High Himalayas, Nepal: An observational study
Exposure to indoor biomass fuel smoke is associated with increased morbidity and mortality. The aim of this study is to evaluate the association between exposure to indoor biomass burning and early... more
The new frontiers of rehabilitation medicine in people with chronic disabling illnesses
Because of the demographic shift and the increased proportion of patients surviving acute critical illnesses, the number of people living with severely disabling chronic diseases and, consequently,... more
Prevalence, predictors and clinical implications of prolonged corrected QT in elderly patients with dementia and suspected syncope
Long QT and use of QT-prolonging drugs are common among older patients receiving polytherapies, but real-world evidence on their impact in clinical practice is controversial. We investigated... more
Assessment of the clinical relevance of pharmacists' interventions performed during medication review in a rheumatology ward
Pharmacists contribute to reduce the number of medication errors during medication review. Nevertheless, few French studies report the potential clinical impact of pharmacists' interventions... more
Non-invasive positive pressure ventilation in pneumonia outside Intensive Care Unit: An Italian multicenter observational study
Non-Invasive Ventilation (NIV) represents a standard of care to treat some acute respiratory failure (ARF). Data on its use in pneumonia are lacking, especially in a setting outside the Intensive... more
Geographical pattern of chronic liver diseases in Italy: Results from two pooled national surveys
The information on the geographical characteristics of chronic liver diseases (CLD) in Italy is out-dated.
Massive cardiac and pulmonary thrombi after cardiac surgery
A 32-year-old obese male with bicuspid aortic valve and severely dilated ascending aorta (59.5 mm) underwent hemi-arch aortic replacement and valvuloplasty on cardiopulmonary bypass. Due to... more
Internal Medicine Flashcard
Papulopustules and paronychia in a lung carcinoma
A 61 years old male was referred from pulmonary medicine department with 2- week history of acneiform lesions over face and upper back, with associated complaints of pain in proximal nail folds of... more
Worsening alopecia in an elderly woman
A woman in her 70s presented with a worsening alopecia and multiple erythematous plaques involving the scalp, the frontal area and the eyebrows (Fig. 1A and B). Pruritus was a significant feature. A... more
Bilateral hand edema: simply nothing or nothing simple?
An 83-year-old Caucasian man presented to the author's hospital for study of hand swelling. The patient presented a bilateral hand dorsal pitting edema (Fig. 1) of one month of evolution with mild... more
An unusual cause of intracranial hemorrhage
A 39-year-old woman with no significant medical history was admitted in the emergency room with loss of consciousness. Computed tomography revealed right-sided putamen hemorrhage (Fig. 1, Panel A).... more
Letter to the Editor
Cannabis as a medicine. An update of the Italian reality
Cannabis and cannabinoids gained increasing attention for their possible clinical uses, as recently reported in a Special issue of this journal. The Mario Negri Institute recently organized a... more
Epidemiology of Clostridium difficile infection in Portugal: Experience at a tertiary care hospital
Clostridium difficile is the main cause of healthcare-associated diarrhoea. Its incidence, severity and relapse rates increased over the past two decades.
Comparison between specific and nonspecific assay in the evaluation of the anticoagulant effect of the Direct Oral Anticoagulants: Our experience in a cardiovascular hospital
The new generation of antithrombotic agents, known as Direct Oral Anticoagulants (DOACs), act on a single factor within the coagulation cascade. Although the monitoring of therapy is not necessary... more
Mortality and morbidity due to exposure to particulate matter related to drying Urmia Lake in the NW Iran
Combination of PM with heavy metals and different constituents related to Urmia Lake and PM from anthropogenic activities has been anticipated to exacerbate health impacts on 3,000,000 inhabitant in... more
Appropriateness of ordering serum angiotensin-converting enzyme during renin-angiotensin-aldosterone system inhibitor therapy
Sarcoidosis is a multisystem inflammatory disease of unknown etiology that manifests as non-caseating granulomas, predominantly in the lungs and intrathoracic lymph nodes, but possibly affecting any... more
Narrative Review
Venous carbon dioxide embolism during laparoscopic cholecystectomy a literature review
Laparoscopy has become the procedure of choice for routine gallbladder removal. A serious complication of this technique is the occurrence of gas emboli due to insufflation. It is associated with a... more
Original Article
Validation of the BAP-65 score for prediction of in-hospital death or use of mechanical ventilation in patients presenting to the emergency department with an acute exacerbation of COPD: a retrospective multi-center study from the Italian Society of...
Exacerbations of chronic obstructive pulmonary disease (COPDE) frequently require hospitalizations, may necessitate of invasive mechanical ventilation (IMV), and are associated with a remarkable in-... more
Atrial fibrillation in patients with active malignancy and use of anticoagulants: Under-prescription but no adverse impact on all-cause mortality
Prescription of anticoagulants (ACs) in patients with cancer and atrial fibrillation (AF) is challenging and the impact on survival is not defined.In this study data prospectively collected in... more
Influence of potassium levels on one-year outcomes in elderly patients with acute heart failure
Abnormal serum potassium levels (K+) in patients with heart failure (HF) relate to worse prognosis. We evaluated whether admission K+ levels predict 1-year outcomes in elderly patients admitted for... more
Cardiac troponin T and NT-proBNP as diagnostic and prognostic biomarkers of primary cardiac involvement and disease severity in systemic sclerosis: A prospective study
The aim of our study was to define the role of high-sensitive cardiac troponin T (hs-cTnT) and NT-proBNP in identifying Systemic Sclerosis (SSc) patients with cardiac involvement and at higher risk... more
Digoxin and prognosis of heart failure in older patients with preserved ejection fraction: Importance of heart rate. Results from an observational and multicenter study
The value of digoxin in heart failure (HF) remains controversial, particularly in patients with preserved ejection fraction (HFpEF). This study evaluated the 1-year risk of events after digoxin... more
Healthcare resource use in XALIA: A subgroup analysis of a non-interventional study of rivaroxaban versus standard anticoagulation for deep vein thrombosis
The non-interventional XALIA study compared the safety and effectiveness of rivaroxaban with standard anticoagulation for the treatment of venous thromboembolism in routine clinical practice. This... more
Association between heat stroke and ischemic heart disease: A national longitudinal cohort study in Taiwan
The purpose of this study is to determine the relationship between heat stroke and ischemic heart disease (IHD), in a nationwide population using a longitudinal approach. We retrospectively examined... more
Review Article
Extrahepatic autoimmunity in autoimmune liver disease
The most important autoimmune liver disease include: autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis. In general, about one in three patients with an autoimmune... more