CME-candidate

Deaths mar atacicept trial for lupus, but research continues

Posted on: 10/07/2014 - 20:55

PARIS – A randomized trial of two doses of atacicept for systemic lupus erythematosus was interrupted after two deaths occurred in patients taking 150 mg of the drug. However, since a post hoc...

Field of Interest: Rheumatology

Type: News Item

Dupilumab produces dramatic improvement in atopic dermatitis

Posted on: 09/07/2014 - 22:00

The monoclonal antibody dupilumab, which blocks the action of the type 2 helper T-cell (Th2) cytokines interleukin-4 and interleukin-13, produced rapid and significant improvement in all signs,...

Field of Interest: Dermatology

Type: News Item

Trial of sirukumab for lupus nephritis falls flat

Posted on: 08/07/2014 - 21:20

PARIS – The investigational interleukin-6 blocker sirukumab provided no benefit to patients with lupus nephritis but put them at a very high risk of developing a serious infection in a small,...

Field of Interest: Rheumatology

Type: News Item

Initial cholecystectomy bests standard approach for suspected common duct stone

Posted on: 08/07/2014 - 21:00

For patients at intermediate risk for having a common duct stone, initial cholecystectomy resulted in a shorter hospital stay, fewer invasive procedures, and no increase in morbidity, compared with...

Field of Interest: Gastroentero...

Type: News Item

No blood clot risk found with HPV vaccination

Posted on: 08/07/2014 - 21:00

The quadrivalent human papillomavirus vaccine does not increase the risk of venous thromboembolism, a study showed. Two previous studies finding an association, one based on the Vaccine Adverse...

Field of Interest: Pulmonology

Type: News Item

Arthritis drug restores hair in man with alopecia universalis and psoriasis

Posted on: 08/07/2014 - 20:00

A 25-year-old man with plaque psoriasis and virtually no hair of any sort now sports a full head of hair plus body hair after treatment with the arthritis drug tofacitinib, according to Dr. Brittany...

Field of Interest: Dermatology

Type: News Item

Arthritis drug restores hair in man with alopecia universalis and psoriasis

Posted on: 08/07/2014 - 20:00

Field of Interest: Rheumatology

Type: News Item

Desonide hydrogel improved itching in atopic dermatitis

Posted on: 08/07/2014 - 18:45

Twice-daily application of 0.05% desonide hydrogel significantly improved clinical symptoms of itching and quality of life scores in 100% of patients with mild to moderate atopic dermatitis after 7...

Field of Interest: Dermatology

Type: News Item

Real-world use supports belimumab clinical trial data

Posted on: 08/07/2014 - 16:20

PARIS – Belimumab produced significant clinical improvement in 74% of patients with systemic lupus erythematosus who took it over a 6-month period, reducing disease symptoms and steroid use and...

Field of Interest: Rheumatology

Type: News Item

Metabolic syndrome, insulin resistance occur frequently in psoriatic arthritis patients

Posted on: 07/07/2014 - 14:35

The metabolic syndrome and insulin resistance are not just common among patients with psoriatic arthritis, but both also correlate with the severity of the inflammatory musculoskeletal disease,...

Field of Interest: Rheumatology

Type: News Item

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