Published: 29 September 2025
Author(s): Kwadwo O. Bonsu, Rufaro S. Chitsike, Tiffany A. Lee, Hai V. Nguyen, Stephanie W. Young
Issue: October 2025
Section: Letter to the Editor

Pulmonary embolism (PE) is a leading cause of cardiovascular morbidity and mortality, with 10–30 % of patients dying within one month of diagnosis [1]. Early risk stratification can aid clinicians in determining the appropriate intensity of treatment and monitoring needed post-discharge [2]. The Pulmonary Embolism Severity Index (PESI) and its simplified version (sPESI) are widely validated tools for estimating 30-day mortality in acute PE [3]. The sPESI score, based on six accessible clinical variables, offers a streamlined alternative with similar prognostic value and is incorporated into international guidelines [2].

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