Published: 28 October 2024
Author(s): Yuting Sun, Hangyu Ji, Wenjie Sun, Xuedong An, Fengmei Lian
Section: Review Article

Insulin resistance (IR) is a metabolic condition in which insulin levels are elevated due to insensitivity to insulin and associated with elevated triglyceride levels. Hypertriglyceridemia leads to increased transport of free fatty acids to the liver, which increases liver sugar production. The Triglyceride-glucose index (TyG index) was first proposed in 2008, and the formula for calculating the TyG index is TyG index = Ln [fasting triglyceride (mg/dl) × fasting glucose (mg/dl) /2]. It is a composite indicator consist of fasting triglyceride (TG) and fasting plasma glucose (FPG) levels [1].

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