Diabetic foot ulceration (DFU), one of the most serious complications of diabetes mellitus (DM), affects 25% of all patients with diabetes and is associated with high morbidity and mortality [1-5]. It is considered a marker for early diagnosis of macro and microvascular complications, neuropathy, immunopathy and foot biomechanics alterations [6]. Managing DFU presents a challenge for the clinician [7-8]. Accordingly, the Infectious Diseases Society of America (IDSA) and the International Working Group on the Diabetic Foot (IWGDF) endorsed a multidisciplinary approach for its management.