Ulcerative colitis (UC) is characterized by an involvement of the large bowel which leads to chronic systemic inflammation, increased aortic stiffness and reflected waves [1–4] and an excess of cardiovascular events [5]. A recent expert panel statement suggests that aortic stiffness is an extraintestinal manifestation of UC caused by chronic inflammation [6]. In this regard, the arterial phenotype of patients with UC is characterized by an increase of both muscular and elastic artery stiffness [7].