Streptococcus gallolyticus and Enterococcus species are members of the gut microbiota and a major cause of infective endocarditis (IE), mainly affecting elderly subjects with digestive or urinary sources of bacteremia [1-4]. Whilst S. gallolyticus causes spontaneous, community-acquired IE, often associated with colorectal disease [5,6], Enterococcal IE more often involves prosthetic valves and associates to health care procedures [3,7]. Whether enterococcal IE is also tied with colorectal diseases, especially colorectal neoplasms (CRN), remains unclear.
