September 2016
23 ArticlesCorrigendum
Corrigendum to “Health care utilization of patients with multiple chronic diseases in The Netherlands: Differences and underlying factors” [Eur. J. Intern. Med. 26 (2015) 190–196]
The authors regret that the printed version of the above article contained a number of errors. A revised, correct and final version has been published online under the same title, with the following... more
Editorial
Risk of ischemic stroke varies by ethnicity in patients with atrial fibrillation: A Swedish national cohort study
AF is an established independent risk factor for ischemic stroke as shown by many previous studies [1]. Anticoagulants are highly effective in reducing the risk of subsequent stroke in AF patients [2... more
Letter to the Editor
Return to sexual activity after myocardial infarction — An analysis of the level of knowledge in men undergoing cardiac rehabilitation
Sexual dysfunction is a typical complication of myocardial infarctions [1] and a high percentage of men limit or cease sexual activity following a myocardial infarction (MI) [2]. The potential... more
Critically ill patients at risk of invasive candidiasis: The “dilemma” of the best antifungal treatment strategy
Dear Editor,
Comparison of the wells score with the revised Geneva score for assessing pretest probability of pulmonary embolism in hospitalized elderly patients
With variable and nonspecific clinical manifestations [1], pulmonary embolism (PE) is associated with a mortality of approximately 30% and may cause sudden death within a few hours [2]. Therefore,... more
Validation of the qSOFA score for identification of septic patients: A retrospective study
Identification of patients with sepsis is a difficult task. Until now, the Systemic Inflammatory Response Syndrome (SIRS) criteria have been recommended to identify patients with significant... more
Pulmonary hypertension in adults with congenital heart disease: First data from Latvian PAH registry
Pulmonary arterial hypertension (PAH) is a common complication in patients with congenital heart disease (CHD), particularly in those with prominent left-to-right (systemic-to-pulmonary) shunt.... more
Response of first line treatment with corticosteroids in a population-based cohort of adults with primary immune thrombocytopenia
Despite therapeutic achievements like rituximab and thrombopoeitin receptor agonists, corticosteroids remain the mainstay of first line treatment for immune thrombocytopenia (ITP) [1,2]. However,... more
Letter: The efficacy and safety of selective granulocyte and monocyte apheresis for inflammatory bowel disease: A meta-analysis
Selective granulocyte and monocyte apheresis (GMA) as a non-pharmacological option, has shown promising efficacy and higher safety in the treatment of patients with ulcerative colitis (UC). The GMA... more
Antineoplastic potential of metformin in colorectal cancer
I read with interest the article “Colon neoplasia in patients with type 2 diabetes on metformin: A meta-analysis” by Rokkas and Portincasa [1]. As the authors note, the mechanisms underlying the... more
Difference in risk assessment for development of contrast-induced acute kidney injury using the MDRD versus CKD-EPI equations to estimate glomerular filtration rate
Patients with kidney disease are at risk to develop acute kidney injury following administration of iodinated contrast. Depending on the estimated glomerular filtration rate (eGFR) and the presence... more
Additional clinical benefit independent of study result or trial arm allocation to participants in multi-center randomized controlled trials
Randomized controlled trials (RCT) are the definitive method for determining primary treatment efficacy and a crucial step in the development of novel therapies. Patients may participate in such... more
Influence of thyroid volume on the effect of methimazole in Japanese subjects with mild Graves' disease
Methimazole (MMI) has been used in subjects with Graves' disease. Although in clinical medicine its starting dose was dependent on the judgment of each physician in charge, the Japan Thyroid... more
Letters to the Editor
Acute effect of dark chocolate on red blood cell distribution width
Evidence accumulated over the past decades attests that moderate consumption of chocolate, especially dark chocolate, may produce favorable effects against cardiovascular disease [1]. Since... more
Narrative Review
Anemia management in cancer patients with chronic kidney disease
Anemia is a common complication of cancer and chronic kidney disease (CKD) associated with decreased physical performance as well as poor prognosis for life expectancy. Renal and cancer-induced... more
Original Article
Diagnostic performance of 320-slice computed tomography coronary angiography for symptomatic patients in clinical practice
Multi-slice computed tomography (MSCT) coronary angiography has been reported as an effective alternative to invasive conventional coronary angiography (CCA) for the diagnosis of coronary artery... more
Heart failure and anemia: Effects on prognostic variables
Anemia is frequent in heart failure (HF), and it is associated with higher mortality. The predictive power of established HF prognostic parameters in anemic HF patients is unknown.
Prospective study of the impact of diabetes mellitus newly diagnosed by glycated hemoglobin on outcomes in patients undergoing percutaneous coronary intervention
We sought to determine the prevalence of diabetes mellitus (DM) newly diagnosed by elevated glycated hemoglobin (HbA1c) in patients undergoing percutaneous coronary intervention (PCI) and its... more
Health care utilization of patients with multiple chronic diseases in the Netherlands: Differences and underlying factors
To examine health care utilization of people with multiple chronic diseases in The Netherlands compared to people with a single chronic disease, and to identify subgroups of multimorbid patients... more
Oxygen therapy in COPD patients with isolated nocturnal hypoxemia; comparison of quality of life and sleep between bronchitis and emphysema phenotype: A prospective observational study
COPD is a heterogeneous disease composed by two main phenotypes: bronchitis (COPDb) and emphysema (COPDe) with different clinical presentation, physiology, imaging, response to therapy and decline in... more
Clinical frailty adds to acute illness severity in predicting mortality in hospitalized older adults: An observational study
Frail individuals may be at higher risk of death from a given acute illness severity (AIS), but this relationship has not been studied in an English National Health Service (NHS) acute hospital... more
Association of glycated hemoglobin with hemoglobin levels in elderly nondiabetic subjects
Glycated hemoglobin (HgbA1C) is being increasingly used for the diagnosis of diabetes mellitus due to its high availability and reproducibility. Several studies have shown that HgbA1C levels may be... more
Review Article
C-reactive protein (CRP) measurement in geriatric patients hospitalized for acute infection
The physiology of inflammatory response is modified by the aging process and is substantially affected by multimorbidity and disability. Infection is the most frequent cause of acute inflammation in... more